The set contains five reagents that induce apoptosis through different mechanisms.
Actinomycin D, an antineoplastic antibiotic, inhibits RNA synthesis. Camptothecin, an inhibitor of nuclear topoisomerase, induces apoptosis in many types of cells. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Etoposide, a derivative of podophyllotoxin, inhibits topoisomerase activity.
Delivery information: Supplied with Actinomycin D, 50 µl (10 mM), violet cap, Camptothecin, 1 ml (2 mM), red cap, Cycloheximide, 1 ml (100 mM), green cap, Dexamethasone, 1 ml (10 mM), blue cap and Etoposide, 100 µl (100 mM), yellow cap.
