Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.
- For Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Recognizes human, mouse, rat, bovine, beluga, dog, chicken, fish, guinea pig, hamster, mouse, monkey, mussel, pig, rabbit, sheep, scallop and Xenopus HSP40 (Hdj1). Detects a band of ~40kDa by Western blot.
Type: Primary
Antigen: HDJ1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
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- Catalog No:
- ENZOADISPA400F
- ENZOADISPA400D
- Antigen symbol:
- HDJ1
- HDJ1
- Antibody type:
- Primary
- Primary
- Clonality:
- Polyclonal
- Polyclonal
- Reactivity:
- Human
- Host:
- Rabbit
- Rabbit
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Form:
- Liquid. In PBS containing 50% glycerol and 0,09% sodium azide.
- Liquid. In PBS containing 50% glycerol and 0,09% sodium azide.
- Purification:
- Protein A affinity purified
- Protein A affinity purified
- Pk
- : ADISPA400D: ENZOADISPA400D
Specifications
Antigen symbolHDJ1Environmentally PreferableAntibody typePrimaryClonalityPolyclonalReactivityHumanHostRabbitIsotypeWestern blotYesImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceYesFormLiquid. In PBS containing 50% glycerol and 0,09% sodium azide.PurificationProtein A affinity purified - : ADISPA400F: ENZOADISPA400F
Specifications
Antigen symbolHDJ1Environmentally PreferableAntibody typePrimaryClonalityPolyclonalReactivityHostRabbitIsotypeWestern blotYesImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceYesFormLiquid. In PBS containing 50% glycerol and 0,09% sodium azide.PurificationProtein A affinity purified