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Specifications
- Antibody type:Primary
- Antigen name:Amyloid beta (A4) Precursor Protein
- Antigen symbol:APP
- Clonality:Polyclonal
- Conjugation:HRP (Horseradish Peroxidase)
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Rabbit,Human,Rat
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Gene ID:351
- Antigen synonyms:CTFgamma|CVAP|ABETA|APPI|AD1|PN-II|ABPP|AAA|PN2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: APP
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Human, Rat, Rabbit