About this item
Recognizes a protein of 40 kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Type: Primary
Antigen: CD7
Clonality: Monoclonal
Clone: C7/511
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human
- Catalog No:
- BNC470511-100
- BNC470511-500
- Antigen symbol:
- CD7
- CD7
- Antigen synonyms:
- TP41|Leu9|T-cell surface antigen Leu-9|T-cell leukemia antigen|Tp40|p41|GP40
- TP41|Leu9|T-cell surface antigen Leu-9|T-cell leukemia antigen|Tp40|p41|GP40
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 647
- CF® 647
- Clone:
- Clone C7/511
- Clone C7/511
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 186820
- 186820
- Isotype:
- IgG2a
- IgG2a
- ImmunoFluorescence:
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Product Information
- Catalog #Supplier #SizePkAvailabilityPrice
- BNC470511-100BNC470511-100100 μL100 µl1 * 100 µl£195.00
Specifications
Antigen symbolCD7Environmentally PreferableAntigen synonymsTP41|Leu9|T-cell surface antigen Leu-9|T-cell leukemia antigen|Tp40|p41|GP40Antibody typePrimaryClonalityMonoclonalConjugationCF® 647CloneClone C7/511ReactivityHumanHostMouseGene ID186820IsotypeIgG2aImmunoFluorescenceYesConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide Specifications
Antigen symbolCD7Environmentally PreferableAntigen synonymsTP41|Leu9|T-cell surface antigen Leu-9|T-cell leukemia antigen|Tp40|p41|GP40Antibody typePrimaryClonalityMonoclonalConjugationCF® 647CloneClone C7/511ReactivityHumanHostMouseGene ID186820IsotypeIgG2aImmunoFluorescenceConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide