This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Type: Primary
Antigen: NEFH
Clonality: Monoclonal
Clone: RT-97
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chicken, Human, Mouse, Pig, Rat
- Catalog No:
- BNC040454-500
- BNC040454-100
- Antigen symbol:
- NEFH
- NEFH
- Antigen name:
- Neurofilament, Heavy Polypeptide
- Neurofilament, Heavy Polypeptide
- Antigen synonyms:
- Neurofilament H|Neurofilament Heavy Polypeptide 200kDa|NEFH|NF-H|Neurofilament Triplet H Protein|NF200
- Neurofilament H|Neurofilament Heavy Polypeptide 200kDa|NEFH|NF-H|Neurofilament Triplet H Protein|NF200
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone RT-97
- Clone RT-97
- Reactivity:
- Pig, Chicken, Human, Rat, Mouse
- Pig, Chicken, Human, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 198760
- 198760
- Isotype:
- IgG1
- IgG1
- ImmunoChemistry:
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
- SizePk
- : BNC040454-500: BTIUBNC040454-500
Specifications
Antigen symbolNEFHAntigen nameNeurofilament, Heavy PolypeptideEnvironmentally PreferableAntigen synonymsNeurofilament H|Neurofilament Heavy Polypeptide 200kDa|NEFH|NF-H|Neurofilament Triplet H Protein|NF200Antibody typePrimaryClonalityMonoclonalConjugationCF® 405SCloneClone RT-97ReactivityPig, Chicken, Human, Rat, MouseHostMouseGene ID198760IsotypeIgG1ImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide - : BNC040454-100: BTIUBNC040454-100
Specifications
Antigen symbolNEFHAntigen nameNeurofilament, Heavy PolypeptideEnvironmentally PreferableAntigen synonymsNeurofilament H|Neurofilament Heavy Polypeptide 200kDa|NEFH|NF-H|Neurofilament Triplet H Protein|NF200Antibody typePrimaryClonalityMonoclonalConjugationCF® 405SCloneClone RT-97ReactivityPig, Chicken, Human, Rat, MouseHostMouseGene ID198760IsotypeIgG1ImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceYesConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide