About this item
The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
The SK7 antibody is a widely used phenotypic marker for human T cells. This antibody may induce T cell activation in the presence of monocytes. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3. Binding of clone SK7 can be blocked by an alternative Anti-Human CD3 clone, OKT3. Please choose the appropriate format for each application.
Type: Primary
Antigen: CD3
Clonality: Monoclonal
Clone: SK7
Conjugation: PE (Phycoerythrin)-Cy7
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Chimpanzee
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Specifications
- Catalog No:
- 60-0036-T100
- 60-0036-T025
- 60-0036-T500
- Antigen symbol:
- CD3E
- CD3E
- CD3E
- Antigen name:
- CD3 Molecule Epsilon
- CD3 Molecule Epsilon
- CD3 Molecule Epsilon
- Antigen synonyms:
- CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
- CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
- CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
- Antibody type:
- Primary
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Monoclonal
- Conjugation:
- PE (Phycoerythrin)-Cy7®
- PE (Phycoerythrin)-Cy7®
- PE (Phycoerythrin)-Cy7®
- Clone:
- SK7
- SK7
- SK7
- Reactivity:
- Chimpanzee, Human
- Chimpanzee, Human
- Chimpanzee, Human
- Host:
- Mouse
- Mouse
- Mouse
- Gene ID:
- 916
- 916
- 916
- Isotype:
- IgG1 kappa
- IgG1 kappa
- IgG1 kappa
- Flow cytometry:
- Yes
- Yes
- Yes
- Storage temperature:
- 2...8 °C, protected from light
- 2...8 °C, protected from light
- 2...8 °C, protected from light
- Tested applications:
- Flow Cytometry
- Flow Cytometry
- Flow Cytometry
Specifications
Product Information
- Catalog #Supplier #PkAvailabilityPrice
- 60-0036-T10060-0036-T100100 Tests1 * 100 Tests£272.00Specifications:
More
Specifications
Antigen symbolCD3EAntigen nameCD3 Molecule EpsilonEnvironmentally PreferableAntigen synonymsCD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chainAntibody typePrimaryClonalityMonoclonalConjugationPE (Phycoerythrin)-Cy7®CloneSK7ReactivityChimpanzee, HumanHostMouseGene ID916IsotypeIgG1 kappaFlow cytometryYesStorage temperature2...8 °C, protected from lightTested applicationsFlow Cytometry - 60-0036-T02560-0036-T02525 Tests1 * 25 Tests£128.00
Specifications
Antigen symbolCD3EAntigen nameCD3 Molecule EpsilonEnvironmentally PreferableAntigen synonymsCD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chainAntibody typePrimaryClonalityMonoclonalConjugationPE (Phycoerythrin)-Cy7®CloneSK7ReactivityChimpanzee, HumanHostMouseGene ID916IsotypeIgG1 kappaFlow cytometryYesStorage temperature2...8 °C, protected from lightTested applicationsFlow Cytometry - 60-0036-T50060-0036-T500500 Tests1 * 500 Tests£1,230.00
Specifications
Antigen symbolCD3EAntigen nameCD3 Molecule EpsilonEnvironmentally PreferableAntigen synonymsCD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chainAntibody typePrimaryClonalityMonoclonalConjugationPE (Phycoerythrin)-Cy7®CloneSK7ReactivityChimpanzee, HumanHostMouseGene ID916IsotypeIgG1 kappaFlow cytometryYesStorage temperature2...8 °C, protected from lightTested applicationsFlow Cytometry